Case Scenario Part VII

Sudbury, MA State Police Crime Laboratory

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July 20, 2017

1. DNA results from the Jim Jones are given below. Determine the frequency of occurrence and the match probability for this profile.

I have posted a solution to a DNA profile in the course resources. You can use this as a guide for your calculations. Please indicate how you arrived at your answers. You can use an excel spreadsheet or do the calculations by hand.

Locus	Allele(p)	Frequency	Allele(q)	Frequency
VWA	14	0.094	15	0.111
TH01	5	0.002	7	0.19
D5S818	10	0.051	11	0.361
D19S433	13	0.253	14	0.369
TPOX	8	0.535	11	0.243
CSF1PO	10	0.217	11	0.301
D3S1358	14	0.103	16	0.235
D7S820	10	0.243	11	0.207
D8S1179	12	0.185	13	0.305
D13S317	11	0.339	12	0.248
D16S539	9	0.113	11	0.321
D18S51	13	0.127	14	0.132
D21S11	28	0.159	30	0.278

2. Watch Richard III: Solving a 500 Year Old Cold Case Dr Turi King TEDxLeicester https://www.youtube.com/watch?v=oyE9sVs_s58

Read the 2014 Nature article by King et al. (2014), Identification of the remains of King Richard III file in Canvas Module 7. There is a supplemental file that may also be helpful.

Answer the following:

a) When and where did Richard III die and where was he laid to rest?

b) Why was his tomb lost to history?

c) Describe his physical appearance.

d) How was his grave rediscovered?

e) How was he killed?

f) What types of evidence were used and integrated that allowed investigators to confidently determine that the remains were those of Richard III?

g) How is false paternity considered more likely than false maternity?

h) Sum up the physical, genealogical, genetic and historical data the indicate the skeleton is Richard III

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